Description
Urea is an organic compound that has been used clinically for dermatological diseases for more than a century. Urea is a potent emollient and keratolytic agent, making urea an effective monotherapy for conditions associated with dry and scaly skin.(6)
Urea plays a significant role in moisture regulation and is a key constituent of natural moisturising factor, the chemical protective coat produced by the epidermis and responsible for keeping the adequate hydration of stratum corneum- the outermost part of the epidermis.